cological Study on Digestive and Bladder Cancer in Relation to the Level of Trihalomethanes in Drinking Water

Llopis-González, A.; Sagrado-Vives, S.; Gimeno-Clemente, N.; Yusà-Pelecha, V.; Martí-Requena, P.; Monforte-Monleón, L.; Morales-Suárez-Varela, M.

doi:10.22059/ijer.2011.368

cological Study on Digestive and Bladder Cancer in Relation to the Level of Trihalomethanes in Drinking Water

Authors

A. Llopis-González ¹

S. Sagrado-Vives ²

N. Gimeno-Clemente ¹

V. Yusà-Pelecha ³

P. Martí-Requena ³

L. Monforte-Monleón ⁴

M. Morales-Suárez-Varela ⁵

¹ Unit of Public Health Department of Preventive Medicine. University of Valencia. Spain, Research group CIBER CB06/02/0045, CIBER actions - Epidemiology and Public Health, Spain

² Department of Analytical Chemistry. University of Valencia, Spain

³ Laboratory of Public Health Center of Valencia. Generalitat Valenciana, Spain

⁴ Aguas de Valencia (AVSA), Gran Vía Marqués del Turia, 19. E-46005 Valencia, Spain

⁵ Unit of Public Health Department of Preventive Medicine. University of Valencia. Spain, Research group CIBER CB06/02/0045, CIBER actions - Epidemiology and Public Health, Spain, Foundation for Investigation. University Hospital Dr. Peset. Valencia, Spain

10.22059/ijer.2011.368

Abstract

omplex mixtures of disinfection by-products are formed in drinking waters when chlorine is used as disinfectant, among which are found trihalomethanes. Trihalomethanes are very stable in the natural environment and are moderately lipophilic. Thus they accumulate in the human organism, which may be related to a greater risk of certain cancers.The objective of this study is to investigate the association between trihalomethanes exposure (e.g. total trihalomethane concentration, TTHM; occurring as chlorination of drinking water) and bladder and certain digestive cancers. Data were collected on different districts inside a Mediterranean city (Valencia, Spain). Samples were analyzed via head-space and electron capture detector to determine TTHM concentrations. The relative influence of different factors has been evaluated. Our results suggest a possible association between bladder cancer in women and trihalomethanes’ exposure at levels below the European Community legal limit; that, at least, advices that such studies deserves more attention.

Keywords

Bladder

Digestive

Cancer

Disinfection

water

Trihalomethanese